Health Effects of Exposure to N2O
Studies have reported adverse health effects for workers exposed to N2O. These include reduced fertility, spontaneous abortion, and neurological, renal and liver disease(1). Patient and clinical staff health effects can also include nausea and vomiting(1). There have been studies on acute and chronic exposure to individuals or groups inside a HCF(4). The results indicate a significant difference in health effects for groups exposed to N2O which include headaches, dizziness, nausea, vomiting, euphoria and tachycardia (heart rate > 100 bpm).
Recent Opinion from the Canadian
Anesthetists Society on N2O Usage
In 2024, the Canadian Anesthesiologists’ Society (CAS) issued their revised edition of Guidelines to the Practice of Anesthesia.(5) In this guideline, Section 10 (page 31 Guidelines for Environmental Sustainability), indicates the following points with regard to N2O:
“The use of desflurane and N2O should be eliminated or minimized to the extent possible given local resources, locations, and the clinical context.”
“Environmentally-friendlier anesthesia techniques such as neuraxial/regional anesthesia and total intravenous anesthesia may be considered as alternatives to volatile inhalational anesthesia to minimize greenhouse gas burden when clinically appropriate, feasible, and available.”